6-Chloro-5-methyl-2-(piperidin-4-yl)benzo[d]oxazole
6-Chloro-5-methyl-2-piperidin-4-yl-1,3-benzoxazole
CAS: 1035840-69-7
Molecular Formula: C13H15ClN2O
6-Chloro-5-methyl-2-(piperidin-4-yl)benzo[d]oxazole - Names and Identifiers
6-Chloro-5-methyl-2-(piperidin-4-yl)benzo[d]oxazole - Physico-chemical Properties
| Molecular Formula | C13H15ClN2O |
| Molar Mass | 250.72 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09701652 |
6-Chloro-5-methyl-2-(piperidin-4-yl)benzo[d]oxazole - Introduction
The 3-benzoxazole is an organic compound containing chloro, methyl, piperidine and benzoxazole groups in its structure.
Nature:
, 3-benzoxazole is a white solid with a high melting point and boiling point. The compound is hardly soluble in water at room temperature, but is soluble in organic solvents such as methanol, ethanol and dichloromethane.
Use:
3-benzoxazole has certain application value in the field of medicine. It can be used as a structural skeleton or group of drug molecules for the synthesis of biologically active compounds, such as antibiotics, anticancer drugs, etc. In addition, the compound is also used as a basic substance in the field of chemical reagents and research.
Preparation Method:
3-benzoxazole can be prepared by a multi-step synthesis reaction, the specific method is as follows:
First, 2-piperidine methanol is reacted with thionyl chloride to produce 2-piperidine methanol sulfoxide salt. Then, 2-piperidine methanol sulfoxide salt is reacted with mercaptophenol to produce 2-piperidinomethoxyphenyl ether. Finally, 2-piperidinomethoxyphenyl ether was reacted with 6-chloro-5-methyl-1, 3-benzoxazole chloride to produce the target product, 3-benzoxazole.
Safety Information:
There is limited data on the safety of 3-benzoxazole. However, in general, the handling of chemicals should follow safe practices. For this compound, it is necessary to avoid contact with the skin, eyes and mucous membranes, and to avoid inhalation of its dust or vapor. Gloves, safety glasses and protective masks should be worn for operation. In the process should pay attention to ventilation, avoid swallowing or inhalation. If exposed or ingested, seek medical attention.
Nature:
, 3-benzoxazole is a white solid with a high melting point and boiling point. The compound is hardly soluble in water at room temperature, but is soluble in organic solvents such as methanol, ethanol and dichloromethane.
Use:
3-benzoxazole has certain application value in the field of medicine. It can be used as a structural skeleton or group of drug molecules for the synthesis of biologically active compounds, such as antibiotics, anticancer drugs, etc. In addition, the compound is also used as a basic substance in the field of chemical reagents and research.
Preparation Method:
3-benzoxazole can be prepared by a multi-step synthesis reaction, the specific method is as follows:
First, 2-piperidine methanol is reacted with thionyl chloride to produce 2-piperidine methanol sulfoxide salt. Then, 2-piperidine methanol sulfoxide salt is reacted with mercaptophenol to produce 2-piperidinomethoxyphenyl ether. Finally, 2-piperidinomethoxyphenyl ether was reacted with 6-chloro-5-methyl-1, 3-benzoxazole chloride to produce the target product, 3-benzoxazole.
Safety Information:
There is limited data on the safety of 3-benzoxazole. However, in general, the handling of chemicals should follow safe practices. For this compound, it is necessary to avoid contact with the skin, eyes and mucous membranes, and to avoid inhalation of its dust or vapor. Gloves, safety glasses and protective masks should be worn for operation. In the process should pay attention to ventilation, avoid swallowing or inhalation. If exposed or ingested, seek medical attention.
Last Update：2024-04-09 21:54:55
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